SOCIO-DEMOGRAPHIC FACTORS AND INTERGENESIC INTERVAL IN NICARAGUAN IMMIGRANT MOTHERS IN COSTA RICA



The HER2-directed antibody-drug conjugate DHES0815A in advanced and/or metastatic breast cancer: preclinical characterization and phase 1 trial results

Abstract Approved antibody-drug conjugates (ADCs) for HER2-positive breast cancer include trastuzumab emtansine and trastuzumab deruxtecan.To develop a differentiated HER2 ADC, we chose an antibody that does not compete with trastuzumab or pertuzumab for binding, conjugated to a reduced potency PBD (pyrrolobenzodiazepine) dimer payload.PBDs are pot

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A typical case of juvenile psammamatoid ossifying fibroma: Case report with literature review and differential diagnosis

Juvenile ossifying fibroma is an uncommon fibro-osseous lesion of jaws nature of short-term rapid growth characterized by excessive growth of bone, destruction, and more probable to reoccur.This lesion has more predominance to occur in younger individuals than older ones and mostly involves facial bones.The lesion mostly involves jaws, orbit, crani

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